Phytochemical Analysis and Cytotoxicity Studies of Curcuma amada rhizomes in BHK-21 Cells
نویسنده
چکیده
Curcuma amada is medicinal plant which is used in several traditional medicines to cure various diseases. Curcuma amada has been shown to possess anti-inflammatory, antioxidant and antitumor properties. In this investigation, it had been planned to study its anticancer properties in BHK-21 cells. Acetone, Methanol, Ethanol and aqueous extracts of the rhizomes of Curcuma amada were screened for their anticancer properties. The cells were seeded with all the extracts separately and then allowed to grow for 24hrs; the cell growth was inhibited within 24hrs. The cytopathology observed were included rounding and clumping of cells, detachment of cells, flagging of cells and apoptosis. Methanolic and ethanolic extracts showed better response than that of its aqueous and acetone extract. The concentration of 10 mg/ml of ethanolic extract inhibited the cancerous cell growth.
منابع مشابه
Pharmacognostical and Phytochemical Studies on Curcuma Amada (linn.) Rhizome (zingiberaceae)
The macroscopic and microscopic characters, physical constant values, extractive values, ash values and the behaviour of powder drug on treatment with different chemical regents, microchemical and histochemical analyses were conducted to characterize some pharmacognostical parameters of Curcuma amada linn. (Zingiberaceae).
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